Pharmacy Prescriptions, Gastrointestinal Meds

Zestoretic (Lisinopril + Hydrochlorothiazide)

Pharmacy Prescriptions, Gastrointestinal Meds » Blood Pressure » Zestoretic (Lisinopril + Hydrochlorothiazide)

Zestoretic (Lisinopril / Hydrochlorothiazide) is an angiotensin converting enzyme (ACE) inhibitor and thiazide diuretic combination used to treat high blood pressure. It may also be used to treat other conditions as determined by your doctor.

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About Zestoretic (Lisinopril + Hydrochlorothiazide):

Product Type: Blood Pressure

Brand name: Zestoretic Generic name: Lisinopril + Hydrochlorothiazide What is the most important information I should know about Zestoretic? • Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant. • Zestoretic may increase the risk of dangerous allergic reactions. Before taking Zestoretic tell your doctor if you have ever had an allergic reaction that involved swelling of your lips face tongue or throat or difficulty breathing. Seek emergency medical attention if you develop any of these symptoms while taking Zestoretic. • Use caution when driving operating machinery or performing other hazardous activities. Zestoretic may cause dizziness or drowsiness. If you experience dizziness or drowsiness avoid these activities. Also use caution when rising from a sitting or lying position. What is Zestoretic? • Zestoretic is a thiazide diuretic (water pill). It increases the amount of salt and water you lose in your urine. Zestoretic is used to lower blood pressure and to decrease edema (swelling). • Zestoretic is in a class of drugs called angiotensin-converting-enzyme inhibitors (ACE inhibitors). Zestoretic is used to lower blood pressure and to relieve the symptoms of congestive heart failure including shortness of breath and swelling of the legs. • Zestoretic is used to treat hypertension (high blood pressure) and to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. • Zestoretic may also be used for purposes other than those listed in this medication guide. Who should not take Zestoretic? • Do not take Zestoretic if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to Zestoretic. • Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant. • Before taking Zestoretic tell your doctor if you have diabetes have gout have a collagen vascular disease such as systemic lupus erythematosus or scleroderma have pancreatitis have kidney disease have liver disease have a blood or bone marrow disease have any type of heart disease or have had a stroke are taking salt substitutes potassium supplements (e.g. K-Dur Klor-Con) or potassium-sparing diuretics such as amiloride (Midamor) triamterene (Dyrenium Dyazide Maxzide) or spironolactone (Aldactone); or are on a salt-restricted diet or have high levels of potassium in your blood. • You may not be able to take Zestoretic or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. • Zestoretic is in the FDA pregnancy category D. This means that Zestoretic is known to harm an unborn baby. When used during the second and third trimesters of pregnancy Zestoretic can cause injury and even death to the developing fetus. Do not take Zestoretic if you are pregnant. • Zestoretic passes into breast milk and may harm a nursing infant. It is not known whether Zestoretic passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. • If you are over 60 years of age you may be more likely to experience side effects from Zestoretic. Your doctor may prescribe a lower dose of this medication. How should I take Zestoretic? • Take Zestoretic exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Do not stop taking this medication without first talking to your doctor. If you stop taking your medication your condition could become worse. • Store Zestoretic at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for your next dose skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Zestoretic overdose include increased urination nausea vomiting diarrhea dizziness fainting weakness fatigue and unconsciousness. What should I avoid while taking Zestoretic? • Use caution when driving operating machinery or performing other hazardous activities. Zestoretic may cause dizziness or drowsiness. If you experience dizziness or drowsiness avoid these activities. Also use caution when rising from a sitting or lying position. • Use alcohol cautiously. Alcohol may further lower blood pressure causing increased drowsiness and dizziness while you are taking Zestoretic. • Avoid a diet high in salt. Too much salt may cause your body to retain water and may decrease the effects of Zestoretic. Ask your doctor or nurse about low-salt diet alternatives. • Do not use salt substitutes or potassium supplements without first talking to your doctor while taking Zestoretic. These products could cause potassium levels in your blood to become dangerously high. • Avoid prolonged exposure to sunlight. Zestoretic may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. • Heavy sweating vomiting diarrhea or other causes of fluid loss may lead to very low blood pressure dizziness and fainting during therapy with Zestoretic. Maintain proper fluid intake to prevent dehydration and related adverse effects. What are the possible side effects of Zestoretic? • If you experience any of the following serious side effects stop taking Zestoretic and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips tongue or face; or hives); fainting spells; unusual fatigue or abnormal bleeding or bruising; yellow skin or eyes; confusion; fever chills or a sore throat; little or no urine; irregular heartbeats; or increased swelling. • Other less serious side effects may be more likely to occur. Continue to take Zestoretic and talk to your doctor if you experience dizziness or lightheadedness; headache; fatigue; tingling or numbness in your arms legs hands or feet; excessive urination; muscle weakness or cramps; increased hunger or thirst; nausea vomiting diarrhea constipation decreased appetite or changes in taste; sensitivity to sunlight; dry tickling cough; anxiety or depression; or itching rash or increased sweating. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Zestoretic? • Before taking Zestoretic tell your doctor if you are taking any of the medicines listed below: a potassium supplement such as K-Dur Klor-Con and others; a salt substitute that contains potassium; another diuretic (water pill) especially triamterene (Dyrenium Maxzide Dyazide) spironolactone (Aldactone) or amiloride (Midamor); cholestyramine (Questran) or colestipol (Colestid); a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin Advil) ketoprofen (Orudis Orudis KT Oruvail) naproxen (Naprosyn Anaprox Aleve) diclofenac (Cataflam Voltaren) etodolac (Lodine) fenoprofen (Nalfon) flurbiprofen (Ansaid) indomethacin (Indocin) ketorolac (Toradol) mefenamic acid (Ponstel) nabumetone (Relafen) oxaprozin (Daypro) piroxicam (Feldene) sulindac (Clinoril) or tolmetin (Tolectin); an oral diabetes medication such as glipizide (Glucotrol) glyburide (Micronase Glynase Diabeta) chlorpropamide (Diabinese) tolazamide (Tolinase) tolbutamide (Orinase) and others; tetracycline (Sumycin others); lithium (Lithane Lithobid Eskalith others); a calcium channel blocker such as amlodipine (Norvasc) diltiazem (Cardizem Dilacor XR Tiazac) nifedipine (Adalat Procardia) verapamil (Calan Verelan Isoptin) and others; doxazosin (Cardura) prazosin (Minipress) or terazosin (Hytrin); reserpine guanadrel (Hylorel) or guanethidine (Ismelin); a nitrate such as nitroglycerin (Nitrostat Transderm-Nitro Nitro-Dur Nitro-Bid Minitran others) isosorbide mononitrate (Imdur ISMO) or isosorbide dinitrate (Isordil Sorbitrate); a pain reliever such as codeine morphine (MS Contin MSIR Roxanol others) propoxyphene (Darvocet Darvon Wygesic) oxycodone (Percocet Percodan) meperidine (Demerol) and others; a barbiturate such as phenobarbital (Luminal Solfoton) amobarbital (Amytal) secobarbital (Seconal) and butabarbital (Butisol); or a steroid medicine such as cortisone (Cortone) dexamethasone (Decadron Hexadrol) betamethasone (Celestone) hydrocortisone (Cortef Hydrocortone) prednisone (Orasone Deltasone) prednisolone (Delta Cortef Prelone) methylprednisolone (Medrol) and others. • You may not be able to take Zestoretic or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Zestoretic or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

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